SHP1 (14D5) Monoclonal Antibody

• Catalog number
  bsm-50269M
• Price
  Please ask
• Size
  0.1ml

• Long name
  SHP1 (14D5) Monoclonal Antibody
• Also known as
  SHP1 (14D5) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SHP1
• Specificity
  This is a highly specific antibody against SHP1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  14D5
• Source
  Recombinant human protein purified from E.coli(His/ABD-SHP1)
• Gene ID number
  5777
• Swiss Prot
  P29350
• Tested Applications
  WB
• Recommended dilutions
  WB (1: 2,000)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
• Purification method
  Ammonium sulfate precipitation
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTPN6; PTP1C
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  SHP1   14D5   Monoclonal  
• Gene symbol
  PTPN6
• Short name
  Anti-SHP1
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1 κ
• Alternative name
  SHP1 (14D5) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9658
• Gene
  PTPN6
• Long gene name
  protein tyrosine phosphatase non-receptor type 6
• Synonyms
  • HCP
  • HCPH
  • PTP-1C
  • SHP-1
  • SHP1
• Locus
  12p13.31
• Discovery year
  1992-02-12
• Entrez gene record
  5777
• Pubmed identfication
  • 1639416
• RefSeq identity
  • NM_002831
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000168518

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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