SERPINB1 Antibody

• Catalog number
  bs-9210R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SERPINB1 Primary Polyclonal Antibody
• Also known as
  SERPINB1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SERPINB1
• Specificity
  This is a highly specific antibody against SERPINB1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SERPINB1
• Gene ID number
  1992
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. The monocyte/neutrophil elastase inhibitor gene, SERPINB1, belongs to the Ov-serpin family (ovalbumin-related serpins). Human SerpinB1, also designated monocyte/neutrophil elastase inhibitor (M/NEI) or leukocyte elastase inhibitor (LEI), is a cytoplasmic protein which acts as a fast-acting stoichiometric proteinase inhibitor that regulates the activity of neutrophil elastase (NE), cathepsin-G and proteinase-3. There are four homologous genes in mouse designated SerpinB1a, SerpinB1b, SerpinB1c and the pseudogene, Serpinb1-ps1. The three protein-coding genes share significant sequence identity, however SerpinB1a (also designated EIA) has been characterized as the functional ortholog of human SerpinB1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Anti elastase; EI; ELANH2; ILEU_HUMAN; LEI; Leukocyte elastase inhibitor; M/NEI; MNEI; Monocyte/neutrophil elastase inhibitor; Peptidase inhibitor 2; Pi-2; PI2; Serine or cysteine proteinase inhibitor clade B ovalbumin member 1; Serpin B1; Serpin peptidase inhibitor clade B ovalbumin member 1; serpinb1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SERPINB1  
• Gene symbol
  SERPINB1
• Short name
  Anti-SERPINB1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SERPINB1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3311
• Gene
  SERPINB1
• Long gene name
  serpin family B member 1
• Synonyms gene
  • ELANH2
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1
  • serpin peptidase inhibitor, clade B (ovalbumin), member 1
• Synonyms
  • EI
  • PI2
  • LEI
  • MNEI
• Synonyms name
  • leukocyte elastase inhibitor
  • monocyte/neutrophil elastase inhibitor
  • anti-elastase
• GenBank acession
  • M93056
• Locus
  6p25.2
• Discovery year
  1993-07-27
• Entrez gene record
  1992
• Pubmed identfication
  • 1376927
  • 24172014
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000014124

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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