SERINC3 Antibody
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Catalog numberbs-5942R
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PricePlease ask
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Size0.1ml
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Long nameSERINC3 Primary Polyclonal Antibody
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Also known asSERINC3 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenSERINC3
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SpecificityThis is a highly specific antibody against SERINC3.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SERINC3
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Gene ID number10955
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenTDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesTMS 1; TMS-1; AIGP1; DF33; SBBI99; serine incorporator 3; TDE; TDE1; Tumor dferentially expressed protein 1; SERC3_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSERINC3
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Short nameAnti-SERINC3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameSERINC3 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetserine incorporator 3, AIGP1 and DIFF33 and SBBI99 and TDE and TDE1 and TMS-1, SERINC3 and IDBG-76679 and ENSG00000132824 and 10955, Plasma membranes, Serinc3 and IDBG-211926 and ENSMUSG00000017707 and 26943, SERINC3 and IDBG-642804 and ENSBTAG00000002187 and 511861
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Gene info
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Identity
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Gene
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Long gene nameserine incorporator 3
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Synonyms gene
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Synonyms gene name
- tumor differentially expressed 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-12-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data