SCN2B Antibody

• Catalog number
  bs-12122R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SCN2B Primary Polyclonal Antibody
• Also known as
  SCN2B PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SCN2B
• Specificity
  This is a highly specific antibody against SCN2B.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SCN2B
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type II beta(sodium channel, voltage-gated, type II, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Neuronal voltage gated sodium channel beta 2 subunit; Scn 2b; Scn2b; SCN2B_HUMAN; Sodium channel beta 2 subunit; Sodium channel subunit beta 2; Sodium channel subunit beta-2; Sodium channel voltage gated type II beta; Sodium channel voltage gated type II beta polypeptide.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SCN2B  
• Gene symbol
  SCN2B
• Short name
  Anti-SCN2B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SCN2B Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10589
• Gene
  SCN2B
• Long gene name
  sodium voltage-gated channel beta subunit 2
• Synonyms gene name
  • sodium channel, voltage-gated, type II, beta polypeptide
  • sodium channel, voltage-gated, type II, beta
  • sodium channel, voltage-gated, type II, beta subunit
  • sodium channel, voltage gated, type II beta subunit
• GenBank acession
  • AY358945
• Locus
  11q23.3
• Discovery year
  1988-11-28
• Entrez gene record
  6327
• Pubmed identfication
  • 10198179
• RefSeq identity
  • NM_004588
• Classification
  • Sodium voltage-gated channel beta subunits
  • V-set domain containing
• VEGA ID
  OTTHUMG00000048248

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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