Scavenger Receptor BII Antibody
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Catalog numberbs-7545R
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PricePlease ask
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Size0.1ml
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Long nameScavenger Receptor BII Antibody
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Also known asScavenger Receptor BII Antibody
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenScavenger Receptor BII
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SpecificityThis is a highly specific antibody against Scavenger Receptor BII.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range222-242/478
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Subcellular locationHelical
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Scavenger Receptor BII
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Gene ID number950
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Swiss ProtQ14108
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenHigh density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesAMRF; EPM4; LGP85; CD36L2; HLGP85; LIMP-2; LIMPII; SR-BII; Lysosome membrane protein 2; 85 kDa lysosomal membrane sialoglycoprotein; CD36 antigen-like 2; Lysosome membrane protein II; LIMP II; Scavenger receptor class B member 2; CD36; SCARB2; LIMP2
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolCACNA1E, SCARB2
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Short nameAnti-Scavenger Receptor BII
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameScavenger Receptor BII Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecalcium voltage-gated channel subunit alpha1 E
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Synonyms gene
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Synonyms gene name
- calcium channel, voltage-dependent, R type, alpha 1E subunit
- calcium voltage-gated channel subunit alpha1 subunit E
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-12-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Calcium voltage-gated channel alpha1 subunits
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namescavenger receptor class B member 2
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Synonyms gene
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Synonyms gene name
- CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data