SAP155 Antibody

• Catalog number
  bs-7417R
• Price
  Please ask
• Size
  0.1ml

• Long name
  SAP155 Primary Polyclonal Antibody
• Also known as
  SAP155 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  SAP155
• Specificity
  This is a highly specific antibody against SAP155.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SAP155/SF3B1
• Gene ID number
  23451
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  SAP 155 is a 1,304 amino acid member of the SF3B1 family and contains eleven HEAT repeats. Localized to nuclear speckles and also to the cytoplasm during mitosis, SAP 155 is a subunit of the SF3B splicing factor. The SF3B splicing factor is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130, SAP 145 and SAP 155. Concomitant with splicing catalysis, SAP 155 is phosphorylated at its N-terminal Thr-Pro dipeptide motifs by Dyrk1A and cyclin E/Cdk2. This modification of SAP 155 is vital for a functional spliceosome as it is an essential event in the basic splicing reaction. Due to alternative splicing events, various SAP 155 isoforms are produced.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Hsh 155; MDS; Pre mRNA processing 10; Pre mRNA splicing factor SF3b 155 kDa subunit; PRP 10; PRP10; PRPF 10; PRPF10; SAP 155; SAP155; SF3B 1; SF3B 1; SF3b155; Spliceosome associated protein 155; Splicing factor 3b subunit 1 155kDa; Splicing factor 3B subunit 1; SF3B1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SAP155  
• Gene symbol
  SF3B1
• Short name
  Anti-SAP155
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  SAP155 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10768
• Gene
  SF3B1
• Long gene name
  splicing factor 3b subunit 1
• Synonyms gene name
  • splicing factor 3b, subunit 1, 155kD
  • splicing factor 3b, subunit 1, 155kDa
• Synonyms
  • SAP155
  • SF3b155
  • PRPF10
  • Prp10
  • Hsh155
• GenBank acession
  • AF054284
• Locus
  2q33.1
• Discovery year
  2000-02-29
• Entrez gene record
  23451
• Pubmed identfication
  • 9585501
• Classification
  • SF3b complex
  • B-WICH chromatin-remodelling complex subunits
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000154447
• Locus Specific Databases
  • LRG_624

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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