SAM68 Antibody
-
Catalog numberbs-13699R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameSAM68 Primary Polyclonal Antibody
-
Also known asSAM68 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenSAM68
-
SpecificityThis is a highly specific antibody against SAM68.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SAM68
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenSam 68 is a protein that is phosphorylated on tyrosine and functions as a substrate for Src family tyrosine kinases during mitosis. Sam 68 also associates with several SH2 and SH3 domain-containing signaling proteins, such as GRB2 and PLC ?. Originally cloned as Ras GAP-associated p62, further investigations have shown that Sam 68 and Ras GAP-associated p62 are not antigenically related, nor are they encoded by the same gene. Like Sam 68, the Sam 68-like mammalian proteins, SLM-1 and SLM-2, demonstrate RNA binding activity. Also like Sam 68, SLM-1 is tyrosine phosphorylated and functions as an adapter protein for signaling molecules, including GRB2, PLC ?, Fyn and Ras GAP. SLM-2 is not tyrosine phosphorylated, nor does it appear to associate with GRB2, PLC ?, Fyn or Ras GAP, indicating that SLM-2 may not be an adapter protein for these proteins.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesFLJ34027; GAP associated tyrosine phosphoprotein p62; GAP-associated tyrosine phosphoprotein p62; KH domain containing RNA binding signal transduction associated 1; KH domain-containing; KHDR1_HUMAN; KHDRBS1; p21 Ras GTPase activating protein associated p62; p21 Ras GTPase-activating protein-associated p62; p62; p68; RNA-binding; Sam68; signal transduction-associated protein 1; Src associated in mitosis 68 kDa protein; Src-associated in mitosis 68 kDa protein.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolKHDRBS1
-
Short nameAnti-SAM68
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameSAM68 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameKH RNA binding domain containing, signal transduction associated 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2002-02-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Signal transduction and activation of RNA metabolism family
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data