RND3 Antibody

• Catalog number
  bs-6095R
• Price
  Please ask
• Size
  0.1ml

• Long name
  RND3 Primary Polyclonal Antibody
• Also known as
  RND3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  RND3
• Specificity
  This is a highly specific antibody against RND3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RND3
• Gene ID number
  390
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The Rho family of proteins mediates cytoskeleton organization and cell motility responses. This family contains twenty different members divided into five groups, the Rho-like, Rac-like, Cdc42-like, Rnd and RhoBTB subfamilies. Rho proteins have GTPase activity and bind GTP in their active form and GDP in their inactive form. In their active form they interact with downstream proteins. However, the Rnd subfamily of proteins containing the Rnd1, Rnd2 and RhoE(Rnd3), binds GTP but not GDP and has no GTPase activity. While Rho proteins are required for stress fibre formation in cultured fibroblasts, epithelial and endothelial cells, overexpression of Rnd3 or Rnd1 in the same cells may cause an opposite effect (i.e. decrease in stress fibre). Thus, the Rnd3 protein may act as an antagonist for the Rho proteins either by directly binding to Rho or to other downstream proteins.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ARHE; memB; Rho family GTPase 3; Rho8; RhoE; RND3_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RND3  
• Gene symbol
  RND3
• Short name
  Anti-RND3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  RND3 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  Rho family GTPase 3, ARHE and memB and Rho8 and RhoE, RND3 and IDBG-72017 and ENSG00000115963 and 390, GTP binding, Plasma membranes, Rnd3 and IDBG-169060 and ENSMUSG00000017144 and 74194, RND3 and IDBG-642057 and ENSBTAG00000039731 and 540224,783333

Gene info

• Identity
  HGNC:671
• Gene
  RND3
• Long gene name
  Rho family GTPase 3
• Synonyms gene
  • ARHE
• Synonyms gene name
  • ras homolog gene family, member E
• Synonyms
  • RhoE
  • Rho8
• Locus
  2q23.3
• Discovery year
  1997-04-16
• Entrez gene record
  390
• Pubmed identfication
  • 8649376
  • 26756630
• RefSeq identity
  • NM_005168
• Classification
  • Rho family GTPases
• VEGA ID
  OTTHUMG00000131859

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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