PTPN11 (246CT9.8.2) Monoclonal Antibody

• Catalog number
  bsm-51075M
• Price
  Please ask
• Size
  0.1ml

• Long name
  PTPN11 (246CT9.8.2) Monoclonal Antibody
• Also known as
  PTPN11 (246CT9.8.2) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PTPN11
• Specificity
  This is a highly specific antibody against PTPN11.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  246CT9.8.2
• Source
  This PTPN11 monoclonal antibody is generated from mouse immunized with PTPN11 recombinant protein.
• Gene ID number
  5781
• Swiss Prot
  Q06124
• Tested Applications
  WB
• Recommended dilutions
  WB(1:100~500)
• Cross reactivity
  Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
• Purification method
  Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; PTP-2C; SHP-2; PTPN11; SHPTP2
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  PTPN11   246CT9   Monoclonal  
• Gene symbol
  PTPN11
• Short name
  Anti-PTPN11
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1 κ
• Alternative name
  PTPN11 (246CT9.8.2) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9644
• Gene
  PTPN11
• Long gene name
  protein tyrosine phosphatase non-receptor type 11
• Synonyms gene
  • NS1
• Synonyms gene name
  • Noonan syndrome 1
  • protein tyrosine phosphatase, non-receptor type 11
• Synonyms
  • BPTP3
  • SH-PTP2
  • SHP-2
  • PTP2C
  • SHP2
• Synonyms name
  • SH2 domain-containing protein tyrosine phosphatase 2
• GenBank acession
  • D13540
• Locus
  12q24.13
• Discovery year
  1993-03-03
• Entrez gene record
  5781
• Pubmed identfication
  • 7894486
  • 1280823
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000134334
• Locus Specific Databases
  • LRG_614

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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