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Long name
PSMD6 Primary Polyclonal Antibody
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Also known as
PSMD6 PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
PSMD6
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Specificity
This is a highly specific antibody against PSMD6.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSMD6
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Gene ID number
5716
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Tested Applications
WB, IHC-P, IF(IHC-P)
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Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. Proteasome 26S S10 is a non-ATPase subunit of the 19S regulator. It acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; KIAA0107; p42A; P44S10; PFAAP4; PSMD6_HUMAN; Phosphonoformate immuno-associated protein 4; Proteasome prosome, macropain 26S subunit, non-ATPase, 6; Proteasome regulatory particle subunit p44S10; Rpn7; S10 antibody SGA-113M; Proteasome 26S S10.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
PSMD6-AS2, PSMD6-AS1, PSMD6
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Short name
Anti-PSMD6
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
PSMD6 Polyclonal Antibody
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Alternative technique
antibodies
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Alternative to gene target
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6, p42A and p44S10 and Rpn7 and S10 and SGA-113M, PSMD6 and IDBG-43018 and ENSG00000163636 and 9861, ATPase activity, nuclei, Psmd6 and IDBG-132715 and ENSMUSG00000021737 and 66413, BT.88479 and IDBG-645134 and ENSBTAG00000015112 and 538625
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