Protein S Antibody

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• Catalog number
  bs-9512R
• Price:

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• Size
  0.1ml

# #

• Long name
  Protein S Primary Polyclonal Antibody
• Also known as
  Protein S PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Protein S
• Specificity
  This is a highly specific antibody against Protein S.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Protein S/PROS
• Gene ID number
  5627
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Protein S (PROS) is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated protein C (APC) and facilitates clearance of early apoptotic cells. In the plasma, circulating Protein S becomes inactive upon complexing with C4b-binding protein (C4BP); 60-70% of Protein S circulates in complex with C4BP. Calcium-dependent association of C4BP-Protein S with apoptotic cells influences the regulation of complement activation. Protein S has APC-independent anticoagulant activity through direct inhibition of prothrombin activation via interactions with Factor X A, Factor V A and phospholipids. Autosomal dominant Protein S deficiency (levels 15 to 37% of normal) correlates with severe recurrent venous thrombosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Preproprotein S; Propiece of latent protein S; PROS 1; PROS; PROS_HUMAN; PROS1; Protein S alpha; Protein Sa; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS21; PS22; PS23; PS24; PS25; PS26; PSA; Vitamin K dependent protein S; Vitamin K-dependent protein S.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

#

• Gene target
  Protein  
• Gene symbol
  PROS1, PROS2P, SKP2
• Short name
  Anti-Protein S
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Protein S Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9456
• Gene
  PROS1
• Long gene name
  protein S
• Synonyms gene
  • PROS
• Synonyms gene name
  • protein S (alpha)
• Locus
  3q11.1
• Discovery year
  1986-01-01
• Entrez gene record
  5627
• Pubmed identfication
  • 214811
  • 1833851
  • 23958677
• RefSeq identity
  • NM_000313
• Classification
  • Gla domain containing
• VEGA ID
  OTTHUMG00000150354
• Locus Specific Databases
  • Protein S Deficiency: A database of Mutations
  • LRG_572

Gene info

• Identity
  HGNC:9458
• Gene
  PROS2P
• Long gene name
  protein S (beta) pseudogene
• Synonyms gene
  • PROS2
  • PROSP
• Synonyms gene name
  • protein S 2
• Locus
  3p11.1
• Discovery year
  1989-05-10
• Entrez gene record
  5628
• Pubmed identfication
  • 2148112
• VEGA ID
  OTTHUMG00000159045

Gene info

• Identity
  HGNC:10901
• Gene
  SKP2
• Long gene name
  S-phase kinase associated protein 2
• Synonyms gene name
  • S-phase kinase-associated protein 2 (p45)
  • S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
• Synonyms
  • FBXL1
  • FBL1
  • p45
• GenBank acession
  • U33761
• Locus
  5p13.2
• Discovery year
  1995-12-18
• Entrez gene record
  6502
• Pubmed identfication
  • 8646875
• RefSeq identity
  • NM_005983
• Classification
  • F-box and leucine rich repeat proteins
• VEGA ID
  OTTHUMG00000131106

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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