Protein C inhibitor Antibody

• Catalog number
  bs-5793R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Protein C inhibitor Primary Polyclonal Antibody
• Also known as
  Protein C inhibitor PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Protein C inhibitor
• Specificity
  This is a highly specific antibody against Protein C inhibitor.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Protein C inhibitor
• Gene ID number
  5104
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Protein C Inhibitor (PCI), a member of the serine protease inhibitor (serpin) superfamily, is abundant in plasma and other body fluids. Protein C Inhibitor inhibits a number of "arginine specific" serine proteases of the coagulation and fibrinolytic systems (including thrombin, trypsin, and activated Protein C), as well as plasma and tissue kallikreins and the sperm protease acrosin. This inhibition is regulated by glycosaminoglycans, such as heparin and heparan sulphate, and several polyanions. As well as its roles in the regulation of hemostasis and fertilisation, Protein C Inhibitor is involved in cell inflammation, proliferation, apoptosis, tumour cell migration, invasion, and metastasis. Recent studies have demonstrated an association between Protein C Inhibitor and multiple sclerosis lesions.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Acrosomal serine protease inhibitor; IPSP; PAI 3; PAI3; PCI; PLANH 3; PLANH3; Plasma serine protease inhibitor; Plasminogen activator inhibitor 3; Plasminogen activator inhibitor III; PROCI; Serpin A5; Serpin peptidase inhibitor clade A alpha 1 antiproteinase antitrypsin member 5; Serpin peptidase inhibitor clade A member 5; SerpinA5; IPSP_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• French translation
  anticorps

• Gene target
  Protein   inhibitor  
• Gene symbol
  PPP1R14C, PPP1R2C, BIRC3
• Short name
  Anti-Protein C inhibitor
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Protein C inhibitor Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14952
• Gene
  PPP1R14C
• Long gene name
  protein phosphatase 1 regulatory inhibitor subunit 14C
• Synonyms gene name
  • protein phosphatase 1, regulatory (inhibitor) subunit 14C
• Synonyms
  • CPI17-like
  • NY-BR-81
  • KEPI
• Synonyms name
  • kinase C-enhanced PP1 inhibitor
• GenBank acession
  • AF308297
• Locus
  6q25.1
• Discovery year
  2001-06-29
• Entrez gene record
  81706
• Pubmed identfication
  • 11948623
• RefSeq identity
  • NM_030949
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000015818

Gene info

• Identity
  HGNC:16324
• Gene
  PPP1R2C
• Long gene name
  PPP1R2C family member C
• Synonyms gene
  • PPP1R2P9
• Synonyms gene name
  • protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
  • protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 9
• Synonyms
  • I-4
• GenBank acession
  • AB044137
• Locus
  Xp11.3
• Discovery year
  2001-08-08
• Entrez gene record
  80316
• Pubmed identfication
  • 11948623
  • 24195737
• VEGA ID
  OTTHUMG00000021382

Gene info

• Identity
  HGNC:591
• Gene
  BIRC3
• Long gene name
  baculoviral IAP repeat containing 3
• Synonyms gene
  • API2
• Synonyms gene name
  • baculoviral IAP repeat-containing 3
• Synonyms
  • cIAP2
  • hiap-1
  • MIHC
  • RNF49
  • MALT2
  • c-IAP2
• Synonyms name
  • apoptosis inhibitor 2
  • TNFR2-TRAF signaling complex protein
  • mammalian IAP homolog C
  • inhibitor of apoptosis protein 1
• GenBank acession
  • L49432
• Locus
  11q22.2
• Discovery year
  1998-06-10
• Entrez gene record
  330
• Pubmed identfication
  • 8552191
  • 8548810
• RefSeq identity
  • NM_001165
• Classification
  • Caspase recruitment domain containing
  • Baculoviral IAP repeat containing
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000167324
• Locus Specific Databases
  • LRG_1423

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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