PQBP1 Antibody

• Catalog number
  bs-11751R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PQBP1 Primary Polyclonal Antibody
• Also known as
  PQBP1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PQBP1
• Specificity
  This is a highly specific antibody against PQBP1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PQBP1
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  38 kDa nuclear protein containing a WW domain; Mental retardation, X linked 55; MRX55; MRXS3; MRXS8; Npw38; Nuclear protein containing WW domain 38 kD; Polyglutamine binding protein 1; Polyglutamine tract binding protein 1; Polyglutamine tract-binding protein 1; Polyglutamine-binding protein 1; PQBP 1; PQBP-1; PQBP1; PQBP1_HUMAN; RENS1; SHS; Sutherland Haan X linked mental retardation syndrome.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PQBP1  
• Gene symbol
  PQBP1
• Short name
  Anti-PQBP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PQBP1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9330
• Gene
  PQBP1
• Long gene name
  polyglutamine binding protein 1
• Synonyms gene
  • RENS1
  • MRXS8
  • SHS
  • MRX55
  • MRX2
  • MRXS3
• Synonyms gene name
  • Sutherland-Haan X-linked mental retardation syndrome
  • mental retardation, X-linked 55
  • mental retardation, X-linked 2 (non-dysmorphic)
• GenBank acession
  • AJ005893
• Locus
  Xp11.23
• Discovery year
  1999-01-12
• Entrez gene record
  10084
• Pubmed identfication
  • 9875212
  • 15024694
  • 14634649
• RefSeq identity
  • NM_001032381.1
• Classification
  • Spliceosomal B complex
• VEGA ID
  OTTHUMG00000024128
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products