POMT1 Antibody

• Catalog number
  bs-5952R
• Price
  Please ask
• Size
  0.1ml

• Long name
  POMT1 Primary Polyclonal Antibody
• Also known as
  POMT1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  POMT1
• Specificity
  This is a highly specific antibody against POMT1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human POMT1
• Gene ID number
  10585
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  POMT1 (Protein O mannosyl transferase 1) is a multipass membrane protein that is found in the endoplasmic reticulum. POMT1 catalyses the transfer of mannosyl residues to the hydroxyl groups of serine or threonine residues. Enzymatic activity is dependent on co expression of POMT1 with POMT2. Defects in the POMT1 gene are associated with Walker-Warburg syndrome (WWS), a congential muscular dystrophy that is associated with mental retardation and is usually lethal within the first few months of life. Other defects in the POMT1 gene result in limb girdle muscular dystrophy type 2K (LGMD2K), which is associated with mild mental retardation. Studies in Drosophila suggest that mutation of POMT1 alters the efficacy of synaptic transmission and a change in subunit composition of post synaptic glutamate receptors at the neuromuscular junction. Missense mutations in POMT1 have been associated with glioneuronal and glial brain tumours.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  POMT1_HUMAN; Protein O-mannosyl-transferase 1; Dolichyl-phosphate-mannose--protein mannosyltransferase 1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  POMT1  
• Gene symbol
  POMT1
• Short name
  Anti-POMT1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  POMT1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9202
• Gene
  POMT1
• Long gene name
  protein O-mannosyltransferase 1
• Synonyms
  • LGMD2K
• Synonyms name
  • dolichyl-phosphate-mannose-protein mannosyltransferase
• GenBank acession
  • AF095136
• Locus
  9q34.13
• Discovery year
  1999-06-25
• Entrez gene record
  10585
• Pubmed identfication
  • 10366449
• RefSeq identity
  • NM_007171
• Classification
  • Dolichyl D-mannosyl phosphate dependent mannosyltransferases
• VEGA ID
  OTTHUMG00000020826
• Locus Specific Databases
  • Leiden Muscular Dystrophy Pages
  • Leiden Muscular Dystrophy pages
  • LRG_842

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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