PMCA1 Antibody

• Catalog number
  bs-4978R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PMCA1 Primary Polyclonal Antibody
• Also known as
  PMCA1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PMCA1
• Specificity
  This is a highly specific antibody against PMCA1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PMCA1
• Gene ID number
  3820
• Tested Applications
  WB, FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Plasma membrane-type Ca2+-ATPases (PMCAs) mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from at least four distinct genes. The expression of different PMCA isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, and with respect to the physiological needs of specific cell and tissue types. Spatial and temporal rates of resting intracellular Ca2+ concentrations and Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export. PMCA1 (ATP2B1) is a ubiquitously expressed form of the PMCA calcium exporter family.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AT2B1_HUMAN; ATP2B1; ATPase Ca++ transporting plasma membrane 1; Plasma membrane calcium ATPase 1; Plasma membrane calcium ATPase isoform 1; Plasma membrane calcium pump isoform 1; Plasma membrane calcium transporting ATPase 1; Plasma membrane calcium-transporting ATPase 1; PMCA 1; PMCA1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PMCA1  
• Gene symbol
  ATP2B1
• Short name
  Anti-PMCA1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PMCA1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:814
• Gene
  ATP2B1
• Long gene name
  ATPase plasma membrane Ca2+ transporting 1
• Synonyms gene name
  • ATPase, Ca++ transporting, plasma membrane 1
• Synonyms
  • PMCA1
• Synonyms name
  • plasma membrane calcium-transporting ATPase 1
• GenBank acession
  • J04027
• Locus
  12q21.33
• Discovery year
  1990-10-05
• Entrez gene record
  490
• Pubmed identfication
  • 1674727
• RefSeq identity
  • NM_001682
• Classification
  • ATPases Ca2+ transporting
• VEGA ID
  OTTHUMG00000169946

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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