PLCZ1 Antibody

• Catalog number
  bs-5378R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PLCZ1 Primary Polyclonal Antibody
• Also known as
  PLCZ1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PLCZ1
• Specificity
  This is a highly specific antibody against PLCZ1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  380-430/608
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PLCZ1
• Gene ID number
  89869
• Swiss Prot
  Q86YW0
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PLCzeta; NYD-SP27; PLC-zeta-1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; Testis-development protein NYD-SP27; PLCZ1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PLCZ1  
• Gene symbol
  PLCZ1
• Short name
  Anti-PLCZ1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PLCZ1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19218
• Gene
  PLCZ1
• Long gene name
  phospholipase C zeta 1
• Synonyms gene name
  • phospholipase C, zeta 1
• Synonyms
  • NYD-SP27
  • PLCzeta
• GenBank acession
  • AY035866
• Locus
  12p12.3
• Discovery year
  2002-09-13
• Entrez gene record
  89869
• Pubmed identfication
  • 12117804
• RefSeq identity
  • NM_033123
• Classification
  • C2 domain containing phospholipases
  • EF-hand domain containing
  • Phospholipases
• VEGA ID
  OTTHUMG00000168937

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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