PLC γ (2B1) Monoclonal Antibody

Catalog number

bsm-50133M
Price:

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Size

0.1ml

Long name

PLC γ (2B1) Monoclonal Antibody
Also known as

PLC γ (2B1) Monoclonal Antibody
Category

Primary Antibodies
Conjugation

Unconjugated
Target Antigen

PLC γ
Specificity

This is a highly specific antibody against PLC γ.
Modification s

None
Modification site s

Unmodified antibody
Clonality

Monoclonal
Clone number

2B1
Concentration

1ug per 1ul
Source

Recombinant human protein purified from E.coli
Gene ID number

5335
Swiss Prot

P19174
Tested Applications

WB, IP
Recommended dilutions

WB (0.1 ug/mL) IP (1.0 ug)
Cross reactivity

Human, Mouse, Rat
Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Purification method

Purified by Protein G.
Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names

PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; Phospholipase C-gamma-1; PLC-gamma-1; PLCG1
Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
French translation

anticorps

Gene target

PLC 2B1 Monoclonal
Gene symbol

PLCB1, PLCL1, PLCG1, PLCH2, PDIA3
Short name

Anti-PLC γ
Technique

Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
Host

Mouse (Mus musculus)
Isotype

Immunoglobulin G (IgG)2a κ
Alternative name

PLC γ (2B1) Monoclonal Antibody
Alternative technique

antibodies

Gene info

Identity

HGNC:15917
Gene

PLCB1
Long gene name

phospholipase C beta 1
Synonyms gene name
- phospholipase C, beta 1 (phosphoinositide-specific)
Synonyms
- KIAA0581
- PLC-I
- PLC154
Synonyms name
- phosphoinositide phospholipase C
GenBank acession
- AB011153
Locus

20p12.3
Discovery year

2001-06-21
Entrez gene record

23236
Pubmed identfication
- 10760467
- 11118617
Classification
- Phospholipases
- C2 domain containing phospholipases
VEGA ID

OTTHUMG00000031849

Gene info

Identity

HGNC:9063
Gene

PLCL1
Long gene name

phospholipase C like 1 (inactive)
Synonyms gene
- PLCE
Synonyms gene name
- phospholipase C, epsilon
- phospholipase C-like 1
- phospholipase C like 1
Synonyms
- PLC-L
- PLCL
- PRIP
- PPP1R127
Synonyms name
- phospholipase C related, but catalytically inactive protein
- protein phosphatase 1, regulatory subunit 127
GenBank acession
- D42108
Locus

2q33.1
Discovery year

1995-12-12
Entrez gene record

5334
Pubmed identfication
- 7633416
RefSeq identity
- NM_006226
Classification
- Protein phosphatase 1 regulatory subunits
- C2 domain containing phospholipases
VEGA ID

OTTHUMG00000132750

Gene info

Identity

HGNC:9065
Gene

PLCG1
Long gene name

phospholipase C gamma 1
Synonyms gene
- PLC1
Synonyms gene name
- phospholipase C, gamma 1 (formerly subtype 148)
- phospholipase C, gamma 1
Synonyms
- PLC148
- PLC-II
- PLCgamma1
- NCKAP3
GenBank acession
- M34667
Locus

20q12
Discovery year

1989-05-31
Entrez gene record

5335
Pubmed identfication
- 2167438
- 3254788
RefSeq identity
- NM_182811
Classification
- Pleckstrin homology domain containing
- MicroRNA protein coding host genes
- Phospholipases
- SH2 domain containing
- C2 domain containing phospholipases
- EF-hand domain containing
VEGA ID

OTTHUMG00000033082

Gene info

Identity

HGNC:29037
Gene

PLCH2
Long gene name

phospholipase C eta 2
Synonyms gene
- PLCL4
Synonyms gene name
- phospholipase C-like 4
- phospholipase C, eta 2
Synonyms
Synonyms name
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2
GenBank acession
- AB007919
Locus

1p36.32
Discovery year

2004-07-28
Entrez gene record

9651
Pubmed identfication
- 15899900
RefSeq identity
- NM_014638
Classification
- EF-hand domain containing
- Phospholipases
VEGA ID

OTTHUMG00000000719

Gene info

Identity

HGNC:4606
Gene

PDIA3
Long gene name

protein disulfide isomerase family A member 3
Synonyms gene
- GRP58
Synonyms gene name
- glucose regulated protein, 58kDa
- protein disulfide isomerase-associated 3
- protein disulfide isomerase family A, member 3
Synonyms
- P58
- ERp61
- ERp57
- ERp60
- GRP57
- PI-PLC
- HsT17083
Locus

15q15.3
Discovery year

1997-06-09
Entrez gene record

2923
Pubmed identfication
- 8974399
RefSeq identity
- NM_005313
Classification
- Protein disulfide isomerases
VEGA ID

OTTHUMG00000044444

MeSH Data

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

PLC γ (2B1) Monoclonal Antibody

Gene info

Gene info

Gene info

Gene info

Gene info

MeSH Data

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Ask Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies PLC γ 2B1 Monoclonal selection audit