PICK1 Antibody
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Catalog numberbs-7898R
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PricePlease ask
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Size0.1ml
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Long namePICK1 Primary Polyclonal Antibody
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Also known asPICK1 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenPICK1
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SpecificityThis is a highly specific antibody against PICK1.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range240-275/415
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Subcellular locationCytoplasm
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PICK1
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Gene ID number9463
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Swiss ProtQ9NRD5
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenProbable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesPICK; PRKCABP; PRKCA-binding protein; Protein interacting with C kinase 1; Protein kinase C-alpha-binding protein; PICK1
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPICK1
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Short nameAnti-PICK1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namePICK1 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetprotein interacting with PRKCA 1, PICK and PRKCABP, PICK1 and IDBG-7244 and ENSG00000100151 and 9463, Arp2/3 complex binding, Cell surfaces, Pick1 and IDBG-161096 and ENSMUSG00000068206 and 102632642,18693, PRKCABP and IDBG-641553 and ENSBTAG00000015268 and 533737
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Gene info
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Identity
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Gene
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Long gene nameprotein interacting with PRKCA 1
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Synonyms gene
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Synonyms gene name
- protein kinase C, alpha binding protein
- protein interacting with PRKCA
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-10-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- AH domain containing
- PDZ domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data