Periaxin Antibody

• Catalog number
  bs-10723R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Periaxin Primary Polyclonal Antibody
• Also known as
  Periaxin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PRX
• Specificity
  This is a highly specific antibody against PRX.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from mousePRX/Periaxin
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]Seems to be required for maintenance of peripheral nerve myelin sheath. May have a role in axon-glial interactions, possibly by interacting with the cytoplasmic domains of integral membrane proteins such as myelin-associated glycoprotein in the periaxonal regions of the Schwann cell plasma membrane. May have a role in the early phases of myelin deposition.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Periaxin; PRX; KIAA1620
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Periaxin  
• Gene symbol
  PRX
• Short name
  Anti-PRX
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Periaxin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13797
• Gene
  PRX
• Long gene name
  periaxin
• Synonyms
  • KIAA1620
• GenBank acession
  • AB046840
• Locus
  19q13.2
• Discovery year
  2001-02-15
• Entrez gene record
  57716
• Pubmed identfication
  • 10839370
  • 9143514
• RefSeq identity
  • NM_020956
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000182597
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_265

MeSH Data

• Name
  Radioimmunosorbent Test
• Concept
  Scope note: Radioimmunoassay of proteins using antibody coupled to an immunosorbent.
• Tree numbers
  • E05.478.566.380.830
  • E05.478.566.639.830
  • E05.601.470.380.830
  • E05.601.470.639.830
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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