PCDHB6 Antibody
-
Catalog numberbs-13726R
-
PricePlease ask
-
Size0.1ml
-
-
Long namePCDHB6 Primary Polyclonal Antibody
-
Also known asPCDHB6 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenPCDHB6
-
SpecificityThis is a highly specific antibody against PCDHB6.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
Subcellular locationExtracellular
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PCDHB6
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenProtocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesPCDH beta6;PCDH beta 6; PCDHB 6; Protocadherin beta 6.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolPCDHB6
-
Short nameAnti-PCDHB6
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative namePCDHB6 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Alternative to gene targetprotocadherin beta 6, PCDHB6 and IDBG-49974 and ENSG00000113211 and 56130, calcium ion binding, Plasma membranes, Pcdhb13 and IDBG-139928 and ENSMUSG00000047307 and 93884, PCDHB6 and IDBG-648650 and ENSBTAG00000047478 and 786512
-
Gene info
-
Identity
-
Gene
-
Long gene nameprotocadherin beta 6
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-06-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Clustered protocadherins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data