PAK2 (Ser20) Antibody

• Catalog number
  bs-3317R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PAK2 (Ser20) Primary Polyclonal Antibody
• Also known as
  PAK2 (Ser20) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PAK2 Ser20
• Specificity
  This is a highly specific antibody against PAK2 Ser20.
• Modification s
  Phosphorylation
• Modification site s
  Ser20
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human PAK2 around the phosphorylation site of Ser20
• Gene ID number
  5062
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, members of which are activated by small molecular weight GTPases. The three most common isoforms are PAK 1, PAK 2, and PAK 3 (also known as alpha PAK, gamma PAK, and beta PAK, respectively). These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, interaction with Src homology 3 (SH3) domains, and caspase mediated proteolytic cleavage. Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), catalyzed by Cdc42, is required for activation of PAK.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  PAK2 phospho S20; PAK2 phospho Ser20; p-PAK2 S20; p-PAK2 Ser20; CB422; EC 2.7.11.1; Gamma PAK; hPAK65; Kinase; p21 CDKN1A-activated kinase 2a; p21 activated kinase 2; p21 protein Cdc42/Rac-activated kinase 2; p21 protein Cdc42 Rac activated kinase 2; p21-activated kinase, 65-KD antibody p21-activated protein kinase I; p21CDKN1A activated kinase 2; p58; p65PAK; PAK 2; PAK65; PAKgamma; S6 H4 kinase; Serine threonine protein kinase PAK 2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PAK2   Ser20  
• Gene symbol
  PAK2
• Short name
  Anti-PAK2 Ser20
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PAK2 (Ser20) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  p21 protein (Cdc42/Rac)-activated kinase 2, PAK65 and PAKgamma, PAK2 and IDBG-71333 and ENSG00000180370 and 5062, transferase activity, nuclei, Pak2 and IDBG-153570 and ENSMUSG00000022781 and 224105, PAK2 and IDBG-634020 and ENSBTAG00000047856 and 513673

Gene info

• Identity
  HGNC:8591
• Gene
  PAK2
• Long gene name
  p21 (RAC1) activated kinase 2
• Synonyms gene name
  • p21 (CDKN1A)-activated kinase 2
  • p21 protein (Cdc42/Rac)-activated kinase 2
• Synonyms
  • PAK65
  • PAKgamma
• Synonyms name
  • S6/H4 kinase
• GenBank acession
  • U24153
• Locus
  3q29
• Discovery year
  1998-03-25
• Entrez gene record
  5062
• Pubmed identfication
  • 7744004
  • 7618083
• RefSeq identity
  • NM_002577
• VEGA ID
  OTTHUMG00000155534

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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