P100 (19AT738.292) Monoclonal Antibody

• Catalog number
  bsm-51014M
• Price
  Please ask
• Size
  0.1ml

• Long name
  P100 (19AT738.292) Monoclonal Antibody
• Also known as
  P100 (19AT738.292) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  P100
• Specificity
  This is a highly specific antibody against P100.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  19AT738.292
• Source
  This monoclonal antibody is generated from mice immunized with four KLH conjugated synthetic peptides selected from human P100.
• Gene ID number
  22974
• Swiss Prot
  Q9ULW0
• Tested Applications
  WB
• Recommended dilutions
  WB(1:100~500)
• Cross reactivity
  Human, Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).
• Purification method
  Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1; Targeting protein for Xklp2; Differentially expressed in cancerous and non-cancerous lung cells 2; Hepatocellular carcinoma-associated antigen 519; Hepatocellular carcinoma-associated antigen 90; Protein fls353; Restricted expression proliferation-associated protein 100; TPX2
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  P100   19AT738   292   Monoclonal  
• Gene symbol
  SND1, TPX2, NFKB2
• Short name
  Anti-P100
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1
• Alternative name
  P100 (19AT738.292) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:30646
• Gene
  SND1
• Long gene name
  staphylococcal nuclease and tudor domain containing 1
• Synonyms
  • TDRD11
  • p100
• Synonyms name
  • p100 EBNA2 co-activator
  • Tudor-SN
• Locus
  7q32.1
• Discovery year
  2006-12-19
• Entrez gene record
  27044
• Pubmed identfication
  • 7651391
  • 9003410
  • 12819296
• RefSeq identity
  • NM_014390
• Classification
  • Tudor domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000157560

Gene info

• Identity
  HGNC:1249
• Gene
  TPX2
• Long gene name
  TPX2 microtubule nucleation factor
• Synonyms gene
  • C20orf2
  • C20orf1
• Synonyms gene name
  • chromosome 20 open reading frame 1
  • TPX2, microtubule-associated, homolog (Xenopus laevis)
  • TPX2, microtubule-associated
• Synonyms
  • p100
  • DIL-2
• GenBank acession
  • AF098158
• Locus
  20q11.21
• Discovery year
  1999-09-29
• Entrez gene record
  22974
• Pubmed identfication
  • 9207457
  • 10393424
• VEGA ID
  OTTHUMG00000032190

Gene info

• Identity
  HGNC:7795
• Gene
  NFKB2
• Long gene name
  nuclear factor kappa B subunit 2
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
• Synonyms
  • LYT-10
  • p52
  • p105
  • NF-kB2
  • p49/p100
• GenBank acession
  • X61498
• Locus
  10q24.32
• Discovery year
  1991-11-14
• Entrez gene record
  4791
• Pubmed identfication
  • 1876189
• Classification
  • IPT domain containing
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000018962
• Locus Specific Databases
  • LRG_1347

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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