NR2E3 Antibody

• Catalog number
  bs-11572R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NR2E3 Primary Polyclonal Antibody
• Also known as
  NR2E3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NR2E3
• Specificity
  This is a highly specific antibody against NR2E3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NR2E3
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Photoreceptor-specific nuclear receptor, also known as NR2E3 or PNR, belongs to a large family of nuclear hormone receptor transcription factors. The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding. NR2E3 has a role in regulating the signaling pathway elemental to the photoreceptor cell function and in regulating pathways involved in embryonic development. NR2E3 is an eye specific nuclear protein found in the outer nuclear layer of the adult retina (where the nuclei of cone and rod photoreceptors are located). Defects in this gene encoding for the protein, which localizes to chromosome 15q22.32, cause enhanced S cone syndrome.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ESCS; ESCS; NR2 E3; Nr2e3; NR2E3_HUMAN; Nuclear receptor subfamily 2 group E member 3; Photoreceptor specic nuclear receptor; Photoreceptor-specic nuclear receptor antibody PNR; Rd 7; rd7; Retina specic nuclear receptor; Retina-specic nuclear receptor; Retinal degeneration 7; Retinal degeneration 7; RNR; RP37.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NR2E3  
• Gene symbol
  NR2E3
• Short name
  Anti-NR2E3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NR2E3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7974
• Gene
  NR2E3
• Long gene name
  nuclear receptor subfamily 2 group E member 3
• Synonyms gene name
  • nuclear receptor subfamily 2, group E, member 3
• Synonyms
  • PNR
  • rd7
  • RP37
• Locus
  15q23
• Discovery year
  1999-09-16
• Entrez gene record
  10002
• Pubmed identfication
  • 10220376
• RefSeq identity
  • NM_014249
• Classification
  • Nuclear receptor subfamily 2 group E
• VEGA ID
  OTTHUMG00000172841
• Locus Specific Databases
  • Mutations of the Photoreceptor cell-specific Nuclear Receptor
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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