NME1 (1172CT2.4.1.1) Monoclonal Antibody
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Catalog number
bsm-51413M
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Price
Please ask
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Size
0.1ml
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Long name
NME1 (1172CT2.4.1.1) Monoclonal Antibody
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Also known as
NME1 (1172CT2.4.1.1) Monoclonal Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
NME1
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Specificity
This is a highly specific antibody against NME1.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Monoclonal
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Clone number
1172CT2.4.1.1
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Source
Purified His-tagged NME1 protein was used to produced this monoclonal antibody.
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Gene ID number
4830
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Swiss Prot
P15531
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Tested Applications
WB, IHC-P
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Recommended dilutions
WB(1:1000), IHC-P(1:25), IHC-P(1:25)
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Cross reactivity
Human, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
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Purification method
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; Nucleoside diphosphate kinase A; NDK A; NDP kinase A; Granzyme A-activated DNase; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; NME1
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translation
anticorps
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Gene target
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Gene symbol
NME1-NME2, NME1, RMRP
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Short name
Anti-NME1
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Technique
Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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Host
Mouse (Mus musculus)
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Alternative name
NME1 (1172CT2.4.1.1) Monoclonal Antibody
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Alternative technique
antibodies
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Alternative to gene target
NME/NM23 nucleoside diphosphate kinase 1, AWD and GAAD and NB and NBS and NDKA and NDPK-A and NDPKA and NM23 and NM23-H1, NME1 and IDBG-409263 and ENSG00000239672 and 4830, poly(A) RNA binding, nuclei, Nme1 and IDBG-208565 and ENSMUSG00000037601 and 18102, NME1 and IDBG-638442 and ENSBTAG00000004651 and 404189
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Gene info
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Identity
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Gene
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Long gene name
NME1-NME2 readthrough
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Synonyms
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GenBank acession
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Locus
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Discovery year
2007-07-31
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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