NKG2D Antibody

• Catalog number
  bs-0938R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NKG2D Primary Polyclonal Antibody
• Also known as
  NKG2D PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NKG2D
• Specificity
  This is a highly specific antibody against NKG2D.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  130-170/215
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from rat NKG2D
• Gene ID number
  24934
• Swiss Prot
  O70215
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  NKG2D; Nkrp2; NKG2-D type II integral membrane protein; Killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NK lectin-like receptor; NKLLR; NKG2-D-activating NK receptor; NKR-P2; CD314; Klrk1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NKG2D  
• Gene symbol
  KLRK1
• Short name
  Anti-NKG2D
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NKG2D Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18788
• Gene
  KLRK1
• Long gene name
  killer cell lectin like receptor K1
• Synonyms gene
  • D12S2489E
• Synonyms gene name
  • DNA segment on chromosome 12 (unique) 2489 expressed sequence
  • killer cell lectin-like receptor subfamily K, member 1
• Synonyms
  • NKG2D
  • KLR
  • NKG2-D
  • CD314
• GenBank acession
  • AJ001687
• Locus
  12p13.2
• Discovery year
  2003-12-12
• Entrez gene record
  22914
• Pubmed identfication
  • 9683661
  • 2007850
• RefSeq identity
  • NM_007360
• Classification
  • Killer cell lectin like receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168574

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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