Nicastrin Antibody
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Catalog numberbs-6058R
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PricePlease ask
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Size0.1ml
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Long nameNicastrin Primary Polyclonal Antibody
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Also known asNicastrin PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenNicastrin
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SpecificityThis is a highly specific antibody against Nicastrin.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range33-83/709
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Nicastrin
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Gene ID number23385
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Swiss ProtQ92542
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenEssential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesATAG1874; Nicastrin; NCSTN; KIAA0253; UNQ1874/PRO4317
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNCSTN, NCSTNP1, NCLN
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Short nameAnti-Nicastrin
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameNicastrin Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namenicastrin
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-02-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namenicastrin pseudogene 1
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Locus
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Discovery year2011-03-17
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenicalin
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Synonyms gene name
- nicalin homolog (zebrafish)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-11-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- M28 metallopeptidases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
- E05.599.495