NGFR Antibody

• Catalog number
  bs-7122R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NGFR Primary Polyclonal Antibody
• Also known as
  NGFR PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NGFR
• Specificity
  This is a highly specific antibody against NGFR.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  170-220/427
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NGFR/p75NTR
• Gene ID number
  4804
• Swiss Prot
  P08138
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The low affinity NGFR (Nerve growth factor receptor) is a 75kDa membrane-spanning glycoprotein lacking intrinsic tyrosine kinase activity. p75NGFR interacts with TrkA, the high affinity NGF receptor and potentiates TrkA signaling at low NGF concentrations. The p75 receptor binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. The p75NGFR plays an important role in neurotrophic factor signaling and has been shown to modulate the susceptibility of selective cellular populations to programmed cell death. It is expressed on many neuronal cells types including many embryonic forms and the receptor can be used to isolate neuronal progenitor cells. NGF is important for the development, differentiation and survival of a variety of neuronal and non-neuronal cells. Its action is mediated by binding to two distinct receptors, the high affinity p140 and low affinity p75. p75NGFR binds neurotrophins including brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5, and NT-6. p75NGFR belongs to the TNF-R superfamily and is reported to mediate NGF-induced apoptosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Gp80 LNGFR; ngfrp75; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; NGF receptor; p75 ICD; CD271; CD271 antigen; Gp80 LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor; Nerve growth factor receptor TNFR superfamily member 16; NGF receptor; NGFR; p75 ICD; p75 Neurotrophin receptor; p75 NTR; TNFR Superfamily Member 16; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; TNR16_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NGFR  
• Gene symbol
  NGFR-AS1, NGFR
• Short name
  Anti-NGFR
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NGFR Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  nerve growth factor receptor, CD271 and Gp80-LNGFR and p75(NTR) and p75NTR and TNFRSF16, NGFR and IDBG-57653 and ENSG00000064300 and 4804, nerve growth factor binding, nuclei, Ngfr and IDBG-209608 and ENSMUSG00000000120 and 18053, NGFR and IDBG-638806 and ENSBTAG00000020979 and 353110

Gene info

• Identity
  HGNC:55555
• Gene
  NGFR-AS1
• Long gene name
  NGFR antisense RNA 1
• Locus
  17q21.33
• Discovery year
  2021-04-07
• Entrez gene record
  100288866
• RefSeq identity
  • NR_103773
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:7809
• Gene
  NGFR
• Long gene name
  nerve growth factor receptor
• Synonyms gene name
  • nerve growth factor receptor (TNFR superfamily, member 16)
• Synonyms
  • TNFRSF16
  • CD271
  • p75NTR
• Synonyms name
  • low affinity nerve growth factor receptor
  • TNFR superfamily, member 16
• GenBank acession
  • M14764
• Locus
  17q21.33
• Discovery year
  2001-06-22
• Entrez gene record
  4804
• Pubmed identfication
  • 3022937
  • 3006050
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000161495

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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