Neuro D2 Antibody

• Catalog number
  bs-11918R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Neuro D2 Primary Polyclonal Antibody
• Also known as
  Neuro D2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Neuro D2
• Specificity
  This is a highly specific antibody against Neuro D2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Neuro D2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  bHLHa1; Class A basic helix-loop-helix protein 1; class A basic helix loop helix protein 1; NDF2_HUMAN; NDR2; NDRF; Neuro-D2; NeuroD-related factor; NeuroD2; Neurogenic dferentiation factor 2; NDF2_HUMAN; neuroD related factor; NeuroD2; neurogenic basic helix loop helix protein; neurogenic dferentiation 2; Neurogenic dferentiation factor 2; neuronal dferentiation 2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  -
• Gene symbol
  FANCD2, SNRPD2, CCND2
• Short name
  Anti-Neuro D2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Neuro D2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3585
• Gene
  FANCD2
• Long gene name
  FA complementation group D2
• Synonyms gene
  • FACD
  • FANCD
• Synonyms gene name
  • Fanconi anemia complementation group D2
• Synonyms
  • FAD
  • FA-D2
• GenBank acession
  • AF340183
• Locus
  3p25.3
• Discovery year
  1996-01-04
• Entrez gene record
  2177
• Pubmed identfication
  • 7581463
  • 11239453
  • 18475298
• Classification
  • FA complementation groups
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000128670
• Locus Specific Databases
  • Fanconi Anaemia Mutation Database
  • Global Variome shared LOVD
  • LRG_306

Gene info

• Identity
  HGNC:11159
• Gene
  SNRPD2
• Long gene name
  small nuclear ribonucleoprotein D2 polypeptide
• Synonyms gene
  • SNRPD1
• Synonyms gene name
  • small nuclear ribonucleoprotein D2 polypeptide (16.5kD)
  • small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
• Synonyms
  • Sm-D2
• Synonyms name
  • snRNP core protein D2
• Locus
  19q13.2-q13.3
• Discovery year
  1990-06-13
• Entrez gene record
  6633
• Pubmed identfication
  • 7527560
  • 1701240
• RefSeq identity
  • NM_004597
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000182130

Gene info

• Identity
  HGNC:1583
• Gene
  CCND2
• Long gene name
  cyclin D2
• Synonyms name
  • G1/S-specific cyclin D2
• GenBank acession
  • AF518005
• Locus
  12p13.32
• Discovery year
  1991-12-10
• Entrez gene record
  894
• Pubmed identfication
  • 1386335
• RefSeq identity
  • NM_001759
• Classification
  • Cyclins
• VEGA ID
  OTTHUMG00000168123

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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