NCKAP1 Antibody
-
Catalog numberbs-6204R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameNCKAP1 Primary Polyclonal Antibody
-
Also known asNCKAP1 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenNCKAP1
-
SpecificityThis is a highly specific antibody against NCKAP1.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 12 NCKAP1
-
Gene ID number10787
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenNAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesNCK associated protein 1; NCK associated protein 1; Membrane associated protein HEM2; Membrane-associated protein HEM-2; NAP 1; NAP1; NAP125; NCK associated protein; Nck-associated protein 1; Nckap1; NCKP1_HUMAN; p125Nap1.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolNCKAP1
-
Short nameAnti-NCKAP1
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameNCKAP1 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Alternative to gene targetNCK-associated protein 1, HEM2 and NAP1 and NAP125 and p125Nap1, NCKAP1 and IDBG-76903 and ENSG00000061676 and 10787, Rac GTPase binding, Plasma membranes, Nckap1 and IDBG-183835 and ENSMUSG00000027002 and 50884, NCKAP1 and IDBG-639791 and ENSBTAG00000033662 and 100300817,101907541
-
Gene info
-
Identity
-
Gene
-
Long gene nameNCK associated protein 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-07-19
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- SCAR/WAVE complex
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data