NAC1/BTBD14B Antibody

• Catalog number
  bs-12247R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NAC1/BTBD14B Primary Polyclonal Antibody
• Also known as
  NAC1/BTBD14B PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NAC1/BTBD14B
• Specificity
  This is a highly specific antibody against NAC1/BTBD14B.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NAC1/BTBD14B
• Gene ID number
  112939
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  NAC1 is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BEND8; BTB Domain Containing 14B; BTB/POZ domain-containing protein 14B; btbd14b; btbd14b; FLJ37383; NAC-1; NAC1; Nacc1; NACC1_HUMAN; Nucleus accumbens-associated protein 1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NAC1/BTBD14B  
• Gene symbol
  NACC1, SCN1A
• Short name
  Anti-NAC1/BTBD14B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NAC1/BTBD14B Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20967
• Gene
  NACC1
• Long gene name
  nucleus accumbens associated 1
• Synonyms gene
  • BTBD14B
• Synonyms gene name
  • BTB (POZ) domain containing 14B
  • nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
• Synonyms
  • NAC1
  • NAC-1
  • BEND8
  • BTBD30
• Synonyms name
  • nucleus accumbens associated 1
  • BEN domain containing 8
• GenBank acession
  • AF395817
• Locus
  19p13.13
• Discovery year
  2003-12-15
• Entrez gene record
  112939
• Pubmed identfication
  • 28132692
• RefSeq identity
  • NM_052876
• Classification
  • BTB domain containing
  • BEN domain containing
• VEGA ID
  OTTHUMG00000180748

Gene info

• Identity
  HGNC:10585
• Gene
  SCN1A
• Long gene name
  sodium voltage-gated channel alpha subunit 1
• Synonyms gene
  • SCN1
  • FEB3
• Synonyms gene name
  • febrile convulsions 3
  • sodium channel, voltage-gated, type I, alpha subunit
  • sodium channel, voltage gated, type I alpha subunit
• Synonyms
  • Nav1.1
  • GEFSP2
  • HBSCI
  • NAC1
  • SMEI
• GenBank acession
  • AB093548
• Locus
  2q24.3
• Discovery year
  1988-11-28
• Entrez gene record
  6323
• Pubmed identfication
  • 8062593
  • 16382098
  • 11823106
• RefSeq identity
  • NM_006920
• Classification
  • Sodium voltage-gated channel alpha subunits
• VEGA ID
  OTTHUMG00000044173
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_8

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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