Myosin VIIa Antibody
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Catalog numberbs-7761R
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PricePlease ask
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Size0.1ml
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Long nameMyosin VIIa Primary Polyclonal Antibody
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Also known asMyosin VIIa PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenMyosin VIIa
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SpecificityThis is a highly specific antibody against Myosin VIIa.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range875-910/2215
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Subcellular locationCytoplasm
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Myosin VIIa
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Gene ID number4647
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Swiss ProtQ13402
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Tested ApplicationsIHC-P, IF(IHC-P)
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Recommended dilutionsIHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenMyosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesDFNB2; MYU7A; NSRD2; USH1B; DFNA11; MYOVIIA; Unconventional myosin-VIIa; MYO7A
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMYO7A, MYRIP
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Short nameAnti-Myosin VIIa
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameMyosin VIIa Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namemyosin VIIA
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Synonyms gene
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Synonyms gene name
- myosin VIIA (Usher syndrome 1B (autosomal recessive, severe))
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-06-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Myosin heavy chains, class VII
- FERM domain containing
- A-kinase anchoring proteins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemyosin VIIA and Rab interacting protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- A-kinase anchoring proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data