MRC2 Antibody

• Catalog number
  bs-6412R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MRC2 Primary Polyclonal Antibody
• Also known as
  MRC2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MRC2
• Specificity
  This is a highly specific antibody against MRC2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  370-420/1479
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MRC2/CD280
• Gene ID number
  9902
• Swiss Prot
  Q9UBG0
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CD280; UPARAP; CLEC13E; ENDO180; C-type mannose receptor 2; C-type lectin domain family 13 member E; Endocytic receptor 180; Macrophage mannose receptor 2; Urokinase-type plasminogen activator receptor-associated protein; UPAR-associated protein; Urokinase receptor-associated protein; MRC2; KIAA0709
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MRC2  
• Gene symbol
  MRC2
• Short name
  Anti-MRC2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MRC2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  mannose receptor, C type 2, CD280 and CLEC13E and ENDO180 and UPARAP, MRC2 and IDBG-63031 and ENSG00000011028 and 9902, carbohydrate binding, Plasma membranes, Mrc2 and IDBG-213230 and ENSMUSG00000020695 and 17534, MRC2 and IDBG-641433 and ENSBTAG00000015739 and 529049

Gene info

• Identity
  HGNC:16875
• Gene
  MRC2
• Long gene name
  mannose receptor C type 2
• Synonyms gene name
  • mannose receptor, C type 2
• Synonyms
  • KIAA0709
  • ENDO180
  • CLEC13E
  • CD280
• Synonyms name
  • C-type lectin domain family 13 member E
  • endocytic receptor 180
• GenBank acession
  • AB014609
• Locus
  17q23.2
• Discovery year
  2002-09-24
• Entrez gene record
  9902
• Pubmed identfication
  • 9734811
  • 8702911
• Classification
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000179178

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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