MEK2(Ser226) Antibody

• Catalog number
  bs-5498R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MEK2(Ser226) Primary Polyclonal Antibody
• Also known as
  MEK2(Ser226) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MEK2 Ser226
• Specificity
  This is a highly specific antibody against MEK2 Ser226.
• Modification s
  Phosphorylation
• Modification site s
  Ser226
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human MEK2 around the phosphorylation site of Ser226
• Gene ID number
  5605
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MAP2K2phospho S226; Cardiofaciocutaneous syndrome; CFC syndrome; Dual specicity mitogen activated protein kinase kinase 2; Dual specicity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; FLJ26075; MAP kinase kinase 2; MAP2K 2; map2k2; MAPK / ERK kinase 2; MAPK/ERK kinase 2; MAPKK 2; MAPKK2; MEK 2; MEK2; Microtubule Associated Protein Kinase Kinase 2; Mitogen activated protein kinase kinase 2; Mitogen activated protein kinase kinase 2 p45; MKK 2; MKK2; MP2K2_HUMAN; OTTHUMP00000165826; OTTHUMP00000165827; PRKMK 2; PRKMK2 V.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MEK2   Ser226  
• Gene symbol
  MAP2K2
• Short name
  Anti-MEK2 Ser226
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MEK2(Ser226) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6842
• Gene
  MAP2K2
• Long gene name
  mitogen-activated protein kinase kinase 2
• Synonyms gene
  • PRKMK2
• Synonyms
  • MEK2
• GenBank acession
  • L11285
• Locus
  19p13.3
• Discovery year
  1993-11-05
• Entrez gene record
  5605
• Pubmed identfication
  • 8388392
• Classification
  • Mitogen-activated protein kinase kinases
• VEGA ID
  OTTHUMG00000134286
• Locus Specific Databases
  • LRG_750

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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