MCP1 Antibody

• Catalog number
  bs-1101R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MCP1 Primary Polyclonal Antibody
• Also known as
  MCP1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MCP1
• Specificity
  This is a highly specific antibody against MCP1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  95-145/148
• Subcellular location
  Secreted
• Source
  KLH conjugated synthetic peptide derived from rat MCP-1
• Gene ID number
  24770
• Swiss Prot
  P14844
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MCP-1; Scya2; Sigje; C-C motif chemokine 2; Immediate-early serum-responsive protein JE; Monocyte chemoattractant protein 1; Monocyte chemotactic protein 1; Small-inducible cytokine A2; Ccl2; Je; Mcp1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MCP1  
• Gene symbol
  CCL2
• Short name
  Anti-MCP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MCP1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10618
• Gene
  CCL2
• Long gene name
  C-C motif chemokine ligand 2
• Synonyms gene
  • SCYA2
• Synonyms gene name
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
  • chemokine (C-C motif) ligand 2
• Synonyms
  • MCP1
  • MCP-1
  • MCAF
  • SMC-CF
  • GDCF-2
  • HC11
  • MGC9434
• Synonyms name
  • monocyte chemotactic protein 1, homologous to mouse Sig-je
  • monocyte chemoattractant protein-1
  • monocyte chemotactic and activating factor
  • monocyte secretory protein JE
  • small inducible cytokine subfamily A (Cys-Cys), member 2
• GenBank acession
  • BC009716
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6347
• Pubmed identfication
  • 2004761
• RefSeq identity
  • NM_002982
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132887

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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