MBNL3 Antibody

• Catalog number
  bs-5721R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MBNL3 Primary Polyclonal Antibody
• Also known as
  MBNL3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MBNL3
• Specificity
  This is a highly specific antibody against MBNL3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MBNL3
• Gene ID number
  55796
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  MBNL3 has been shown to inhibit muscle differentiation. MBNL3 belongs to a highly conserved family of tissue-specific alternative splicing regulators. This family is known to regulate terminal muscle differentiation through alternative splicing control and several groups have suggested that the family participates in the differentiation of photoreceptors, neurons, adipocytes and blood cell types. MBNL3 is expressed in myoblasts, muscle precursor cells, and during the early stages of myogenesis, but is detected at very low levels in terminally differentiated myotubes. MBNL proteins have been shown to sequester foci of expanded-repeat transcripts and are thought to therefore play a role in the molecular pathology of a group of neuromuscular diseases including the Myotonic Dystrophies.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MBLX; CHCR; Cys3His CCG1 required protein; MBLX39; MBNL 3; MBXL; Muscleblind like protein 3; Muscleblind like X linked protein; Protein HCHCR; MBNL3_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MBNL3  
• Gene symbol
  MBNL3
• Short name
  Anti-MBNL3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MBNL3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20564
• Gene
  MBNL3
• Long gene name
  muscleblind like splicing regulator 3
• Synonyms gene name
  • muscleblind-like 3 (Drosophila)
  • muscleblind-like splicing regulator 3
• Synonyms
  • CHCR
  • FLJ11316
  • MBLX39
  • MBXL
• GenBank acession
  • AF491305
• Locus
  Xq26.2
• Discovery year
  2003-03-05
• Entrez gene record
  55796
• Pubmed identfication
  • 12297108
  • 10970838
• RefSeq identity
  • NM_018388
• Classification
  • Zinc fingers CCCH-type
• VEGA ID
  OTTHUMG00000022426
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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