MASTL (235CT7.8.2.3) Monoclonal Antibody

• Catalog number
  bsm-51071M
• Price
  Please ask
• Size
  0.1ml

• Long name
  MASTL (235CT7.8.2.3) Monoclonal Antibody
• Also known as
  MASTL (235CT7.8.2.3) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MASTL
• Specificity
  This is a highly specific antibody against MASTL.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  235CT7.8.2.3
• Source
  This MASTL monoclonal antibody is generated from mouse immunized with MASTL recombinant protein.
• Gene ID number
  84930
• Swiss Prot
  Q96GX5
• Tested Applications
  WB
• Recommended dilutions
  WB(1:1000~16000)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro; however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.
• Purification method
  Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  GW; GWL; THC2; MAST-L; GREATWALL; Serine/threonine-protein kinase greatwall; hGWL; Microtubule-associated serine/threonine-protein kinase-like; MASTL
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  MASTL   235CT7   Monoclonal  
• Gene symbol
  MASTL
• Short name
  Anti-MASTL
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1 κ
• Alternative name
  MASTL (235CT7.8.2.3) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19042
• Gene
  MASTL
• Long gene name
  microtubule associated serine/threonine kinase like
• Synonyms gene name
  • microtubule associated serine/threonine kinase-like
• Synonyms
  • FLJ14813
  • THC2
  • Gwl
• Synonyms name
  • greatwall kinase homolog
• GenBank acession
  • BC009107
• Locus
  10p12.1
• Discovery year
  2004-02-10
• Entrez gene record
  84930
• RefSeq identity
  • NM_032844
• Classification
  • AGC family kinases
• VEGA ID
  OTTHUMG00000017855

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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