MAGOH Antibody
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Catalog numberbs-11882R
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PricePlease ask
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Size0.1ml
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Long nameMAGOH Primary Polyclonal Antibody
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Also known asMAGOH PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenMAGOH
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SpecificityThis is a highly specific antibody against MAGOH.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAGOH
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenMAGOH, the human homolog of Drosophila mago nashi, is required for embryo development. MAGOH is ubiquitously expressed in adult tissues. It has an unusual structure consiting of an extremely flat, six-stranded anti-parallel β sheet packed next to two helices. MAGOH interacts with the Y14 protein to form a complex that plays a crucial role in postsplicing processing (including nuclear export and cytoplasmic localization of the mRNA) and in the nonsense-mediated mRNA decay (NMD) surveillance process. The MAGOH-Y14 complex remains persistently associated in the same position on the mRNA after its export to the cytoplasm and requires translation of the mRNA for removal. This complex may illustrate the mechanism of the pre-mRNA splicing machinery for forming a stable exon-exon junction complex-mRNA at splice junctions.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesMago nashi homolog proliferation associated Drosophila; Mago nashi protein homolog ; magoh; MGN_HUMAN; Protein mago nashi homolog.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMAGOH-DT, MAGOH
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Short nameAnti-MAGOH
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameMAGOH Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameMAGOH divergent transcript
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Locus
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Discovery year2021-08-02
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Entrez gene record
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RefSeq identity
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene namemago homolog, exon junction complex subunit
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Synonyms gene name
- mago-nashi (Drosophila) homolog, proliferation-associated
- mago-nashi homolog, proliferation-associated (Drosophila)
- mago homolog, exon junction complex core component
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-02-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Spliceosomal P complex
- Exon junction complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data