LGR6 Antibody
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Catalog numberbs-8609R
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PricePlease ask
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Size0.1ml
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Long nameLGR6 Primary Polyclonal Antibody
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Also known asLGR6 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenLGR6
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SpecificityThis is a highly specific antibody against LGR6.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range430-480/967
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LGR6
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Gene ID number59352
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Swiss ProtQ9HBX8
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesGPCR; VTS20631; Leucine-rich repeat-containing G-protein coupled receptor 6; LGR6; UNQ6427/PRO213
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolLGR6
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Short nameAnti-LGR6
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameLGR6 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameleucine rich repeat containing G protein-coupled receptor 6
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein-coupled receptors, Class A orphans
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data