LDHA (AF14A11) Monoclonal Antibody

• Catalog number
  bsm-50391M
• Price
  Please ask
• Size
  0.1ml

• Long name
  LDHA (AF14A11) Monoclonal Antibody
• Also known as
  LDHA (AF14A11) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  LDHA
• Specificity
  This is a highly specific antibody against LDHA.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  AF14A11
• Concentration
  1ug per 1ul
• Source
  Recombinant human protein purified from E.coli (His-LDHA)
• Gene ID number
  3939
• Swiss Prot
  P00338
• Tested Applications
  WB, IP
• Recommended dilutions
  WB (0.1 ug/mL) IP (2.0 ug)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84–89% sequence similarities and 69–75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers.
• Purification method
  Purified by Protein G.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  LDHM; GSD11; PIG19; HEL-S-133P; L-lactate dehydrogenase A chain; LDH-A; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59; LDHA
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  LDHA   AF14A11   Monoclonal  
• Gene symbol
  LDHA
• Short name
  Anti-LDHA
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)2b κ
• Alternative name
  LDHA (AF14A11) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6535
• Gene
  LDHA
• Long gene name
  lactate dehydrogenase A
• GenBank acession
  • X02152
• Locus
  11p15.1
• Discovery year
  2001-06-22
• Entrez gene record
  3939
• Pubmed identfication
  • 3000353
• RefSeq identity
  • NM_005566
• VEGA ID
  OTTHUMG00000167721

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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