KAT5 (Ser90) Antibody

• Catalog number
  bs-17097R
• Price
  Please ask
• Size
  0.1ml

• Long name
  KAT5 (Ser90) Primary Polyclonal Antibody
• Also known as
  KAT5 (Ser90) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  KAT5
• Specificity
  This is a highly specific antibody against KAT5.
• Modification s
  Phosphorylation
• Modification site s
  Ser90
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  80-99/513
• Subcellular location
  Nucleus, Helical
• Source
  KLH conjugated synthesised phosphopeptide derived from human KAT5 around the phosphorylation site of Ser90
• Gene ID number
  10524
• Swiss Prot
  Q92993
• Tested Applications
  WB
• Recommended dilutions
  WB(1:100-1000)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2. Promotes FOXP3 acetylation and positively regulates its transcriptional repressor activity (PubMed:17360565).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; ZC2HC5; HTATIP1; Histone acetyltransferase KAT5; 60 kDa Tat-interactive protein; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting protein; KAT5
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KAT5   Ser90  
• Gene symbol
  KAT5
• Short name
  Anti-KAT5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  KAT5 (Ser90) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  K(lysine) acetyltransferase 5, cPLA2 and ESA1 and HTATIP and HTATIP1 and PLIP and TIP and TIP60 and ZC2HC5, KAT5 and IDBG-57604 and ENSG00000172977 and 10524, transferase activity, nuclei, Kat5 and IDBG-132192 and ENSMUSG00000024926 and 81601, KAT5 and IDBG-644226 and ENSBTAG00000005578 and 505619

Gene info

• Identity
  HGNC:5275
• Gene
  KAT5
• Long gene name
  lysine acetyltransferase 5
• Synonyms gene
  • HTATIP
• Synonyms gene name
  • HIV-1 Tat interactive protein, 60kDa
  • K(lysine) acetyltransferase 5
• Synonyms
  • TIP60
  • PLIP
  • cPLA2
  • HTATIP1
  • ESA1
  • ZC2HC5
• Synonyms name
  • Tat interacting protein, 60kDa
  • K-acetyltransferase 5
• GenBank acession
  • U74667
• Locus
  11q13.1
• Discovery year
  2000-04-13
• Entrez gene record
  10524
• Pubmed identfication
  • 8607265
• RefSeq identity
  • NM_006388
• Classification
  • Zinc fingers C2HC-type
  • MYST type domain containing lysine acetyltransferases
• VEGA ID
  OTTHUMG00000166617

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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