HSPB2 Antibody

• Catalog number
  bs-4782R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HSPB2 Primary Polyclonal Antibody
• Also known as
  HSPB2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HSPB2
• Specificity
  This is a highly specific antibody against HSPB2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  110-160/182
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSPB2
• Gene ID number
  3316
• Swiss Prot
  Q16082
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB2 (heat shock 27 kDa protein 2), also known as HSP 27 or MKBP, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle. Localized to mitochondria, HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death. HSPB2 is abundantly expressed in several cancer cell lines, suggesting that HSPB2 may be an important factor in tumor transformation and metastasis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MKBP; HSP27; Hs.78846; LOH11CR1K; Heat shock protein beta-2; HspB2; DMPK-binding protein
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HSPB2  
• Gene symbol
  HSPB2-C11orf52, HSPB2
• Short name
  Anti-HSPB2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HSPB2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:41996
• Gene
  HSPB2-C11orf52
• Long gene name
  HSPB2-C11orf52 readthrough (NMD candidate)
• Locus
  11q23.1
• Discovery year
  2011-05-31
• Entrez gene record
  100528019
• RefSeq identity
  • NR_037651.1
• VEGA ID
  OTTHUMG00000166887

Gene info

• Identity
  HGNC:5247
• Gene
  HSPB2
• Long gene name
  heat shock protein family B (small) member 2
• Synonyms gene name
  • heat shock 27kD protein 2
  • heat shock 27kDa protein 2
• Synonyms
  • Hs.78846
  • MKBP
• GenBank acession
  • U75898
• Locus
  11q23.1
• Discovery year
  1997-12-23
• Entrez gene record
  3316
• Pubmed identfication
  • 9344664
  • 9490724
• Classification
  • Small heat shock proteins
• VEGA ID
  OTTHUMG00000166886

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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