HP1 (Tyr24) Antibody
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Catalog numberbs-0928R
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PricePlease ask
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Size0.1ml
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Long nameHP1 (Tyr24) Primary Polyclonal Antibody
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Also known asHP1 (Tyr24) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenHP1 Tyr24
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SpecificityThis is a highly specific antibody against HP1 Tyr24.
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Modification sPhosphorylation
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Modification site sTyr24
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr24
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Gene ID number34119
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityOther Species
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Cross reactive species detailsFruit Fly
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Background of the target antigenHP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are requiredfor binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesHeterochromatin protein 1; HP1; Non-histone chromosomal protein C1A9 antigen; CG8409
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCBX5, HP1BP3, CBX1, TFF1
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Short nameAnti-HP1 Tyr24
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameHP1 (Tyr24) Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namechromobox 5
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Synonyms gene name
- chromobox homolog 5 (Drosophila HP1 alpha)
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox homolog 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameheterochromatin protein 1 binding protein 3
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Synonyms gene name
- heterochromatin protein 1, binding protein 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-05-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namechromobox 1
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Synonyms gene name
- chromobox homolog 1 (Drosophila HP1 beta)
- chromobox homolog 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametrefoil factor 1
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Synonyms gene
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Synonyms gene name
- breast cancer, estrogen-inducible sequence expressed in
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data