HNF1 beta Antibody
-
Catalog numberbs-8617R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameHNF1 beta Primary Polyclonal Antibody
-
Also known asHNF1 beta PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenHNF1 beta
-
SpecificityThis is a highly specific antibody against HNF1 beta.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HNF1 beta
-
Gene ID number6928
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenHNF-1 (a and b), HNF-3 (a, b and g), HNF-4 (a and g) and HNF-6 compose, in part, a homoeprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. HNF-3a, HNF-3b and HNF-3g regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3a and HNF-3b have also been shown to be involved in gastrulation events such as body axis formation. HNF-4a and HNF-4g have been shown to be important for early embryo development. HNF-4a is expressed in liver, kidney, pancreas, small intestine, testis and colon; and HNF-4g is expressed in each of these tissues except liver. HNF-6 has been shown to bind to the promoter of HNF-3b, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation. Evidence suggests that HNF-6 may also be a transriptional activator for at least 22 other hepatocyte-enriched genes, including cytochrome P450 2C13 and a-1 antitrypsin.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesFJHN; Hepatocyte nuclear factor 1 beta; Hepatocyte nuclear factor 1-beta; HNF 1B; HNF 2; HNF-1-beta; HNF-1B; HNF1B; HNF1 beta; HNF1 homeobox B; HNF1B; HNF1B_HUMAN; HNF1beta; HNF2; Homeoprotein LF B3; Homeoprotein LFB3; HPC11; LF B3; LFB3; MODY 5; MODY5; TCF 2; TCF 2 protein; TCF-2; TCF2; TCF2 protein; Transcription factor 2; Transcription factor 2 hepatic; Variant hepatic nuclear factor 1; Variant hepatic nuclear factor; VHNF 1; vHNF1.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolHNF1A
-
Short nameAnti-HNF1 beta
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameHNF1 beta Polyclonal Antibody
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameHNF1 homeobox A
-
Synonyms gene
-
Synonyms gene name
- transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1990-02-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- HNF class homeoboxes
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data