HLA B27 Antibody

• Catalog number
  bs-8604R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HLA B27 Primary Polyclonal Antibody
• Also known as
  HLA B27 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HLA B27
• Specificity
  This is a highly specific antibody against HLA B27.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HLA B27
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Major histocompatibility complex (MHC) molecules form an integral part of the immune response system. They are cell-surface receptors that bind peptides and present them to T lymphocytes. Human leukocyte antigens (HLAs) are polymorphic members of the MHC family that are specifically involved in the presentation of antigens to the T cell receptor. There are two classes of HLA antigens: class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Class I molecules are expressed in nearly all cells and play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-B encodes a membrane anchored heavy chain which hetero-dimerizes with a light chain (∫-2-Microglobulin) to form MHC-I. Polymorphisms yield hundreds of HLA-B alleles. The HLA-B27 allele appears with increased frequency in uveitis patients.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  HLA B27 HLA-B27; HLAB; Leukocyte antigen class I B; Lymphocyte antigen; Major histocompatibility complex class I B; SPDA1; 1B27_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HLA   B27  
• Gene symbol
  HLA-DPA2, HLA-DOA, HLA-DQA1, HLA-N, HLA-DPB1, HLA-DQA2, HLA-DQB2, HLA-W, HLA-DRA, HLA-S
• Short name
  Anti-HLA B27
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HLA B27 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4939
• Gene
  HLA-DPA2
• Long gene name
  major histocompatibility complex, class II, DP alpha 2 (pseudogene)
• Synonyms gene
  • HLA-DP2A
• GenBank acession
  • X01634
• Locus
  6p21.32
• Discovery year
  1986-01-01
• Entrez gene record
  646702
• Pubmed identfication
  • 6597088
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031061
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:4936
• Gene
  HLA-DOA
• Long gene name
  major histocompatibility complex, class II, DO alpha
• Synonyms gene
  • HLA-DZA
  • HLA-DNA
• Synonyms
  • HLA-D0-alpha
• GenBank acession
  • M31525
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3111
• Pubmed identfication
  • 2370084
• RefSeq identity
  • NM_002119
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031211
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:4942
• Gene
  HLA-DQA1
• Long gene name
  major histocompatibility complex, class II, DQ alpha 1
• Synonyms gene
  • HLA-DQA
• Synonyms
  • CELIAC1
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3117
• RefSeq identity
  • NM_002122
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031106
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:19406
• Gene
  HLA-N
• Long gene name
  major histocompatibility complex, class I, N (pseudogene)
• Synonyms
  • HLA-30
• GenBank acession
  • M96329
• Locus
  6p22.1
• Discovery year
  2002-10-23
• Entrez gene record
  267014
• Pubmed identfication
  • 10452889
  • 1517563
• RefSeq identity
  • NG_009940
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031167
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:4940
• Gene
  HLA-DPB1
• Long gene name
  major histocompatibility complex, class II, DP beta 1
• Synonyms gene
  • HLA-DP1B
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3115
• RefSeq identity
  • NM_002121
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031076
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:4943
• Gene
  HLA-DQA2
• Long gene name
  major histocompatibility complex, class II, DQ alpha 2
• Synonyms gene
  • HLA-DXA
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3118
• RefSeq identity
  • NM_020056
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031108
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:4945
• Gene
  HLA-DQB2
• Long gene name
  major histocompatibility complex, class II, DQ beta 2
• Synonyms gene
  • HLA-DXB
• GenBank acession
  • M83890
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3120
• Pubmed identfication
  • 2564844
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031125
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:23425
• Gene
  HLA-W
• Long gene name
  major histocompatibility complex, class I, W (pseudogene)
• Synonyms gene
  • HLA-80
• Synonyms gene name
  • HLA-80 pseudogene
• GenBank acession
  • M96334
• Locus
  6p22.1
• Discovery year
  2004-01-16
• Entrez gene record
  352966
• Pubmed identfication
  • 10557312
  • 1517563
• RefSeq identity
  • NG_015995
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031242
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:4947
• Gene
  HLA-DRA
• Long gene name
  major histocompatibility complex, class II, DR alpha
• Synonyms gene
  • HLA-DRA1
• Locus
  6p21.32
• Discovery year
  2001-06-22
• Entrez gene record
  3122
• RefSeq identity
  • NM_019111
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031269
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:19395
• Gene
  HLA-S
• Long gene name
  major histocompatibility complex, class I, S (pseudogene)
• Synonyms
  • HLA-17
• GenBank acession
  • M96339
• Locus
  6p21.33
• Discovery year
  2002-10-23
• Entrez gene record
  267015
• Pubmed identfication
  • 10452889
  • 1517563
• RefSeq identity
  • NG_009941
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031178
• Locus Specific Databases
  • IMGT/HLA Database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products