HEXDC Antibody

• Catalog number
  bs-8418R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HEXDC Primary Polyclonal Antibody
• Also known as
  HEXDC PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HEXDC
• Specificity
  This is a highly specific antibody against HEXDC.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HEXDC
• Gene ID number
  284004
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Beta hexosaminidase D; Beta N acetylhexosaminidase; FLJ23825; Hexosaminidase glycosyl hydrolase family 20 catalytic domain containing; hexosaminidase glycosyl hydrolase family 20, catalytic domain; Hexosaminidase D; Hexosaminidase domain containing protein; N acetyl beta galactosaminidase; HEXDC_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HEXDC  
• Gene symbol
  HEXD, HEXD-IT1
• Short name
  Anti-HEXDC
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HEXDC Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:26307
• Gene
  HEXD
• Long gene name
  hexosaminidase D
• Synonyms gene
  • HEXDC
• Synonyms gene name
  • hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
• Synonyms
  • FLJ23825
• Synonyms name
  • hexosaminidase D, cytosolic
• GenBank acession
  • AK074405
• Locus
  17q25.3
• Discovery year
  2006-01-12
• Entrez gene record
  284004
• Pubmed identfication
  • 19040401
• RefSeq identity
  • NM_173620
• Classification
  • Hexosaminidases
• VEGA ID
  OTTHUMG00000178836

Gene info

• Identity
  HGNC:43650
• Gene
  HEXD-IT1
• Long gene name
  HEXD intronic transcript 1
• Synonyms gene
  • HEXDC-IT1
• Synonyms gene name
  • HEXDC intronic transcript 1 (non-protein coding)
  • HEXDC intronic transcript 1
• GenBank acession
  • AK129961
• Locus
  17q25.3
• Discovery year
  2011-12-19
• Entrez gene record
  100505970
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000178837

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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