HDC2/PHC2 Antibody

• Catalog number
  bs-11291R
• Price
  Please ask
• Size
  0.1ml

• Long name
  HDC2/PHC2 Primary Polyclonal Antibody
• Also known as
  HDC2/PHC2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  HDC2/PHC2
• Specificity
  This is a highly specific antibody against HDC2/PHC2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HDC2/PHC2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Early development regulatory protein 2;hPH2;early development regulator 2 (homolog of polyhomeotic 2);Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development. PHC2 (polyhomeotic-like protein 2), also known as early development regulatory protein 2, is an 858 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Phosphorylated upon DNA damage, PHC2 contains one SAM (sterile alpha motif) domain and one FCS-type zinc finger.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Early development regulatory protein 2; hPH2; early development regulator 2 homolog of polyhomeotic 2; early development regulator 2 like; EDR2; MGC163502; mph2; PH2; PHC2; PHC2_HUMAN; polyhomeotic 2; polyhomeotic like 2; Polyhomeotic-like protein 2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HDC2/PHC2  
• Gene symbol
  PHC2-AS1, PHC2
• Short name
  Anti-HDC2/PHC2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  HDC2/PHC2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40205
• Gene
  PHC2-AS1
• Long gene name
  PHC2 antisense RNA 1
• Locus
  1p35.1
• Discovery year
  2019-09-19
• Entrez gene record
  101929464
• RefSeq identity
  • NR_125978
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3183
• Gene
  PHC2
• Long gene name
  polyhomeotic homolog 2
• Synonyms gene
  • EDR2
• Synonyms gene name
  • early development regulator 2 (homolog of polyhomeotic 2)
  • polyhomeotic-like 2 (Drosophila)
  • polyhomeotic homolog 2 (Drosophila)
• Synonyms
  • HPH2
• GenBank acession
  • AJ419231
• Locus
  1p35.1
• Discovery year
  1997-09-12
• Entrez gene record
  1912
• Pubmed identfication
  • 9121482
  • 12384788
• RefSeq identity
  • NM_198040
• Classification
  • Sterile alpha motif domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000004133

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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