Girdin (Tyr1765) Antibody

• Catalog number
  bs-13358R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Girdin (Tyr1765) Primary Polyclonal Antibody
• Also known as
  Girdin (Tyr1765) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Girdin Tyr1765
• Specificity
  This is a highly specific antibody against Girdin Tyr1765.
• Modification s
  Phosphorylation
• Modification site s
  Tyr1765
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human APE around the phosphorylation site of Ser1765
• Gene ID number
  55704
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Girdin is a 1,871 amino acid protein that, via interactions with phosphoinositides, localizes to the cell membrane and to the cytosol. Expressed ubiquitously, girdin functions to enhance the activity of PI 3-kinase-dependent phosphorylation of proteins, such as Akt1, thereby inducing the phosphorylation of downstream protein targets and, ultimately, regulating DNA replication and cellular proliferation. Additionally, girdin is crucial for cell migration and is responsible for both maintaining the structural integrity of the Actin cytoskeleton and for regulating the formation of Actin stress fibers. Girdin exists as a homodimer that can itself be phosphorylated—an event that delocalizes girdin from the cell membrane, thus allowing it to participate in cell migration events. Two isoforms of girdin exist due to alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Girdin phospho Y1765; p-Girdin phospho Y1765; Akt phosphorylation enhancer; APE; Coiled coil domain containing protein 88A; G alpha interacting vesicle associated protein; Girders of actin filament; GIV; HkRP1; Hook related protein 1; AKT iphosphorylation enhancer; Akt phosphorylation enhancer; Ccdc88a; GIV; GRDN; GRDN_HUMAN; HkRP1; Hook related protein 1; Hook-related protein 1; KIAA1212.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Girdin   Tyr1765  
• Short name
  Anti-Girdin Tyr1765
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Girdin (Tyr1765) Polyclonal Antibody
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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