GGT1 Antibody

• Catalog number
  bs-2976R
• Price
  Please ask
• Size
  0.1ml

• Long name
  GGT1 Primary Polyclonal Antibody
• Also known as
  GGT1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  GGT1
• Specificity
  This is a highly specific antibody against GGT1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  380-430/569
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GGT1
• Gene ID number
  2678
• Swiss Prot
  P19440
• Tested Applications
  WB, FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  GGT; GTG; CD224; GGT 1; D22S672; D22S732; Gamma-glutamyltranspeptidase 1; Gamma-glutamyltransferase 1; Glutathione hydrolase 1; Leukotriene-C4 hydrolase; GGT1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GGT1  
• Gene symbol
  GGT1
• Short name
  Anti-GGT1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  GGT1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4250
• Gene
  GGT1
• Long gene name
  gamma-glutamyltransferase 1
• Synonyms gene
  • GGT
• Synonyms
  • D22S672
  • D22S732
  • CD224
• GenBank acession
  • M24903
• Locus
  22q11.23
• Discovery year
  1986-01-01
• Entrez gene record
  2678
• Pubmed identfication
  • 8104871
  • 18357469
• RefSeq identity
  • NM_013430
• Classification
  • CD molecules
  • Gamma-glutamyltransferases
• VEGA ID
  OTTHUMG00000030859

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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