GAS2 Antibody

• Catalog number
  bs-13289R
• Price
  Please ask
• Size
  0.1ml

• Long name
  GAS2 Primary Polyclonal Antibody
• Also known as
  GAS2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  GAS2
• Specificity
  This is a highly specific antibody against GAS2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GAS2
• Gene ID number
  2620
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells. Gas2 is believed to also be involved in the membrane ruffling process. During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues. Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles. Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, lung and kidney. There is no evidence, however, of Gas2 expression in spleen.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  GAS 2; GAS-2; Gas2; GAS2_HUMAN; Growth arrest specic 2; Growth arrest specic protein 2; Growth arrest-specic protein 2; MGC32610.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GAS2  
• Gene symbol
  GAS2
• Short name
  Anti-GAS2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  GAS2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  growth arrest-specific 2, GAS2 and IDBG-36228 and ENSG00000148935 and 2620, protein binding, Plasma membranes, Gas2 and IDBG-188499 and ENSMUSG00000030498 and 14453, GAS2 and IDBG-642237 and ENSBTAG00000021654 and 614840

Gene info

• Identity
  HGNC:4167
• Gene
  GAS2
• Long gene name
  growth arrest specific 2
• GenBank acession
  • BC040470
• Locus
  11p14.3
• Discovery year
  1997-08-28
• Entrez gene record
  2620
• Pubmed identfication
  • 9521882
• RefSeq identity
  • NM_177553
• VEGA ID
  OTTHUMG00000166071

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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