GARNL1 Antibody

• Catalog number
  bs-13286R
• Price
  Please ask
• Size
  0.1ml

• Long name
  GARNL1 Primary Polyclonal Antibody
• Also known as
  GARNL1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  GARNL1
• Specificity
  This is a highly specific antibody against GARNL1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GARNL1
• Gene ID number
  253959
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  GARNL1 is expressed during embryogenesis with E12. During development, GARNL1 expression decreases, persisting at high levels only in neurons of the adult brain. GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap. GARNL1 is imported to the nucleus via dimerization with E12. GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes. This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12. GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades. In adult brain, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  DKFZp566D133; DKFZp667F074; GAP related interacting partner to E12; GARN L1; GARNL 1; GRIPE; GTPase activating Rap/RanGAP domain like 1; KIAA0884; Tuberin like protein 1; TULIP 1. TULIP1; RGPA1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GARNL1  
• Gene symbol
  RALGAPA1
• Short name
  Anti-GARNL1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  GARNL1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17770
• Gene
  RALGAPA1
• Long gene name
  Ral GTPase activating protein catalytic subunit alpha 1
• Synonyms gene
  • GARNL1
• Synonyms gene name
  • GTPase activating RANGAP domain-like 1
  • GTPase activating Rap/RanGAP domain-like 1
• Synonyms
  • GRIPE
  • DKFZp667F074
  • KIAA0884
  • Tulip1
  • RalGAPalpha1
• Synonyms name
  • tuberin-like protein 1
  • GAP-related interacting protein to E12
• GenBank acession
  • AK126975
• Locus
  14q13.2
• Discovery year
  2003-10-09
• Entrez gene record
  253959
• Pubmed identfication
  • 19520869
• RefSeq identity
  • NM_001283043
• VEGA ID
  OTTHUMG00000170619

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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